International Prognostic Scoring System (IPSS)
Greenberg, P., Cox, C., LeBeau et al. International scoring system for evaluating prognosis in myelodysplastic syndromes. Blood 1997; 89, 2079-2088.
| Prognostic variable | 0 | 0.5 | 1 (Score value) | 1.5 | 2 |
| Bone marrow blasts (%) | <5 | 5 - 10 | - | 11 - 20 | 21 - 30 |
| Karyotype* | Good | Intermediate | Poor | ||
| Cytopenias | 0-1 | 2 - 3 | - |
*Good: normal, -Y, del(5q), del(20q)
Poor: chromosome 7 anomalies or complex (≥3 abnormalities)
Intermediate: other abnormalities.
Cytopenias defined as haemoglobin concentration <100 g/l, neutrophils <1.8 x 109/l and platelets <100 x 109/l
IPSS Prognostic Risk Categories/Scores
| RISK | SCORE |
| Low | 0 |
| Intermediate - 1 | 0.5 - 1 |
| Intermediate - 2 | 1.5 - 2 |
| High | ≥2.5 |
